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PS128 can benefit our nervous system and entire body.

The strain is being studied around the world for a range of applications.





Before being granted GRAS (Generally Recognized As Safe) designation, qualified experts must agree that scientific data and information about the substance establishes the safety of its intended use. Lactobacillus plantarum PS128 is self-affirmed for GRAS status in 2020.

Safety Test Results

The National Yang-Ming University Institute of Food Safety and Health Risk Assessment was commissioned to carry out the following safety tests for PS128:

PS128 is identified as Lactiplantibacillus plantarum [1], generally recognized as safe for consumption by major regulatory bodies.

PS128 is not genotoxic nor resistant to antibiotics [2]. It meets EFSA food safety standards.

None of PS128's many human and animal trials has shown significant negative side effects from using the strain.

[1] Liu, W. H., Yang, C. H., Lin, C. T., Li, S. W., Cheng, W. S., Jiang, Y. P., Wu, C. C., Chang, C. H., & Tsai, Y. C. (2015). Genome architecture of Lactobacillus plantarum PS128, a probiotic strain with potential immunomodulatory activity. Gut pathogens, 7, 22.

[2] Liao, P. L., Wu, C. C., Chen, T. Y., Tsai, Y. C., Peng, W. S., Yang, D. J., & Kang, J. J. (2019). Toxicity Studies of Lactobacillus plantarum PS128TM Isolated from Spontaneously Fermented Mustard Greens. Foods (Basel, Switzerland), 8(12), 668.

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